Selection and Identification of Skeletal-Muscle-Targeted RNA Aptamers

Oligonucleotide gene therapy has shown great promise for the treatment of muscular dystrophies. Nevertheless, the selective delivery to affected muscles has shown to be challenging because of their high representation in the body and the high complexity of their cell membranes. Current trials show l...

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Detalles Bibliográficos
Autores principales: Philippou, Styliana, Mastroyiannopoulos, Nikolaos P., Makrides, Neoklis, Lederer, Carsten W., Kleanthous, Marina, Phylactou, Leonidas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862129/
https://www.ncbi.nlm.nih.gov/pubmed/29499933
http://dx.doi.org/10.1016/j.omtn.2017.12.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862129/
https://www.ncbi.nlm.nih.gov/pubmed/29499933
http://dx.doi.org/10.1016/j.omtn.2017.12.004

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