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Selection and Identification of Skeletal-Muscle-Targeted RNA Aptamers
Oligonucleotide gene therapy has shown great promise for the treatment of muscular dystrophies. Nevertheless, the selective delivery to affected muscles has shown to be challenging because of their high representation in the body and the high complexity of their cell membranes. Current trials show l...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862129/ https://www.ncbi.nlm.nih.gov/pubmed/29499933 http://dx.doi.org/10.1016/j.omtn.2017.12.004 |