Gender-related prognostic value and genomic pattern of intra-tumor heterogeneity in colorectal cancer

Intra-tumor heterogeneity (ITH) is crucial in tumorigenesis and resistance to target therapy. Here, we used mutant-allele tumor heterogeneity (MATH) to measure ITH based on next-generation sequencing data and high MATH was proven as an independent risk prognostic factor in male CRC patients in both...

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Detalles Bibliográficos
Autores principales: Zhang, Jieyun, Yan, Shican, Liu, Xiyu, Gan, Lu, Wu, Zhenhua, Gong, Yiwei, Huang, Mingzhu, Zhang, Xiaowei, Guo, Weijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Manuscript
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862243/
https://www.ncbi.nlm.nih.gov/pubmed/28531253
http://dx.doi.org/10.1093/carcin/bgx046

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