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A systematic evaluation of normalization methods in quantitative label-free proteomics

To date, mass spectrometry (MS) data remain inherently biased as a result of reasons ranging from sample handling to differences caused by the instrumentation. Normalization is the process that aims to account for the bias and make samples more comparable. The selection of a proper normalization met...

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Detalles Bibliográficos
Autores principales: Välikangas, Tommi, Suomi, Tomi, Elo, Laura L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862339/
https://www.ncbi.nlm.nih.gov/pubmed/27694351
http://dx.doi.org/10.1093/bib/bbw095