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Linear-In-Flux-Expressions Methodology: Toward a Robust Mathematical Framework for Quantitative Systems Pharmacology Simulators

Quantitative Systems Pharmacology (QSP) modeling is increasingly used as a quantitative tool for advancing mechanistic hypotheses on the mechanism of action of a drug, and its pharmacological effect in relevant disease phenotypes, to enable linking the right drug to the right patient. Application of...

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Detalles Bibliográficos
Autores principales:	McQuade, Sean T, Abrams, Ruth E, Barrett, Jeffrey S, Piccoli, Benedetto, Azer, Karim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862386/ https://www.ncbi.nlm.nih.gov/pubmed/29581702 http://dx.doi.org/10.1177/1177625017711414

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