CCR2 antagonism leads to marked reduction in proteinuria and glomerular injury in murine models of focal segmental glomerulosclerosis (FSGS)

Focal segmental glomerulosclerosis (FSGS) comprises a group of uncommon disorders that present with marked proteinuria, nephrotic syndrome, progressive renal failure and characteristic glomerular lesions on histopathology. The current standard of care for patients with FSGS include immunosuppressive...

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Detalles Bibliográficos
Autores principales: Miao, Zhenhua, Ertl, Linda S., Newland, Dale, Zhao, Bin, Wang, Yu, Zang, Xiaoping, Campbell, James J., Liu, Xiaoli, Dang, Ton, Miao, Shichang, Krasinski, Antoni, Punna, Sreenivas, Zeng, Yibin, McMahon, Jeffrey, Zhang, Penglie, Charo, Israel F., Schall, Thomas J., Singh, Rajinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862408/
https://www.ncbi.nlm.nih.gov/pubmed/29561839
http://dx.doi.org/10.1371/journal.pone.0192405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862408/
https://www.ncbi.nlm.nih.gov/pubmed/29561839
http://dx.doi.org/10.1371/journal.pone.0192405

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