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Development and validation of a physiology-based model for the prediction of pharmacokinetics/toxicokinetics in rabbits
The environmental fates of pharmaceuticals and the effects of crop protection products on non-target species are subjects that are undergoing intense review. Since measuring the concentrations and effects of xenobiotics on all affected species under all conceivable scenarios is not feasible, standar...
Autores principales: | Mavroudis, Panteleimon D., Hermes, Helen E., Teutonico, Donato, Preuss, Thomas G., Schneckener, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862475/ https://www.ncbi.nlm.nih.gov/pubmed/29561908 http://dx.doi.org/10.1371/journal.pone.0194294 |
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