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Association of traffic air pollution and rhinitis quality of life in Peruvian children with asthma

BACKGROUND: Air pollution exposure may contribute to rhinoconjunctivitis morbidity in children with underlying airways disease. Prior studies have not assessed rhinoconjunctivitis-related quality of life (QOL) in children with asthma chronically exposed to air pollution. METHODS: Children ages 9–19...

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Autores principales: Bose, Sonali, Romero, Karina, Psoter, Kevin J., Curriero, Frank C., Chen, Chen, Johnson, Caroline M., Kaji, Deepak, Breysse, Patrick N., Williams, D’Ann L., Ramanathan, Murugappan, Checkley, William, Hansel, Nadia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862476/
https://www.ncbi.nlm.nih.gov/pubmed/29561906
http://dx.doi.org/10.1371/journal.pone.0193910
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author Bose, Sonali
Romero, Karina
Psoter, Kevin J.
Curriero, Frank C.
Chen, Chen
Johnson, Caroline M.
Kaji, Deepak
Breysse, Patrick N.
Williams, D’Ann L.
Ramanathan, Murugappan
Checkley, William
Hansel, Nadia N.
author_facet Bose, Sonali
Romero, Karina
Psoter, Kevin J.
Curriero, Frank C.
Chen, Chen
Johnson, Caroline M.
Kaji, Deepak
Breysse, Patrick N.
Williams, D’Ann L.
Ramanathan, Murugappan
Checkley, William
Hansel, Nadia N.
author_sort Bose, Sonali
collection PubMed
description BACKGROUND: Air pollution exposure may contribute to rhinoconjunctivitis morbidity in children with underlying airways disease. Prior studies have not assessed rhinoconjunctivitis-related quality of life (QOL) in children with asthma chronically exposed to air pollution. METHODS: Children ages 9–19 years with asthma from peri-urban Peru, self-reporting rhinoconjunctivitis symptoms (n = 484), were administered the Rhinoconjunctivitis QOL Questionnaire (RQLQ) at repeated intervals over one year, with scores dichotomized into bothered (>0) and not bothered (= 0). Individual weekly exposures to particulate matter<2.5μm (PM(2.5)) and its black carbon (BC) component were estimated by inverse distance weighted methods. Generalized estimating equations, adjusting for covariates, estimated associations of PM(2.5) and BC with QOL. RESULTS: Participants were on average 13 years old, 55% female, and majority were atopic (77%). Mean (SD) PM(2.5) and BC concentrations were 21(3.2) μg/m3 and 4.4(1.5) μg/m3, respectively. In adjusted multi-pollutant models, each 10μg/m3 increase in PM(2.5) was associated with increased odds of worse rhinoconjunctivitis QOL (OR;[95% CI]: 1.83;[1.33,2.52]). A 10% increase in the BC proportion was associated with higher rhinitis burden (OR;[95% CI]: 1.80;[1.22,2.66]), while increases in the non-BC component of PM did not significantly impact rhinoconjunctivitis QOL. Associations were similar regardless of atopy. CONCLUSION: Higher PM2.5 and BC exposure is associated with worse rhinitis QOL among asthmatic children.
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spelling pubmed-58624762018-03-28 Association of traffic air pollution and rhinitis quality of life in Peruvian children with asthma Bose, Sonali Romero, Karina Psoter, Kevin J. Curriero, Frank C. Chen, Chen Johnson, Caroline M. Kaji, Deepak Breysse, Patrick N. Williams, D’Ann L. Ramanathan, Murugappan Checkley, William Hansel, Nadia N. PLoS One Research Article BACKGROUND: Air pollution exposure may contribute to rhinoconjunctivitis morbidity in children with underlying airways disease. Prior studies have not assessed rhinoconjunctivitis-related quality of life (QOL) in children with asthma chronically exposed to air pollution. METHODS: Children ages 9–19 years with asthma from peri-urban Peru, self-reporting rhinoconjunctivitis symptoms (n = 484), were administered the Rhinoconjunctivitis QOL Questionnaire (RQLQ) at repeated intervals over one year, with scores dichotomized into bothered (>0) and not bothered (= 0). Individual weekly exposures to particulate matter<2.5μm (PM(2.5)) and its black carbon (BC) component were estimated by inverse distance weighted methods. Generalized estimating equations, adjusting for covariates, estimated associations of PM(2.5) and BC with QOL. RESULTS: Participants were on average 13 years old, 55% female, and majority were atopic (77%). Mean (SD) PM(2.5) and BC concentrations were 21(3.2) μg/m3 and 4.4(1.5) μg/m3, respectively. In adjusted multi-pollutant models, each 10μg/m3 increase in PM(2.5) was associated with increased odds of worse rhinoconjunctivitis QOL (OR;[95% CI]: 1.83;[1.33,2.52]). A 10% increase in the BC proportion was associated with higher rhinitis burden (OR;[95% CI]: 1.80;[1.22,2.66]), while increases in the non-BC component of PM did not significantly impact rhinoconjunctivitis QOL. Associations were similar regardless of atopy. CONCLUSION: Higher PM2.5 and BC exposure is associated with worse rhinitis QOL among asthmatic children. Public Library of Science 2018-03-21 /pmc/articles/PMC5862476/ /pubmed/29561906 http://dx.doi.org/10.1371/journal.pone.0193910 Text en https://creativecommons.org/publicdomain/zero/1.0/ This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication.
spellingShingle Research Article
Bose, Sonali
Romero, Karina
Psoter, Kevin J.
Curriero, Frank C.
Chen, Chen
Johnson, Caroline M.
Kaji, Deepak
Breysse, Patrick N.
Williams, D’Ann L.
Ramanathan, Murugappan
Checkley, William
Hansel, Nadia N.
Association of traffic air pollution and rhinitis quality of life in Peruvian children with asthma
title Association of traffic air pollution and rhinitis quality of life in Peruvian children with asthma
title_full Association of traffic air pollution and rhinitis quality of life in Peruvian children with asthma
title_fullStr Association of traffic air pollution and rhinitis quality of life in Peruvian children with asthma
title_full_unstemmed Association of traffic air pollution and rhinitis quality of life in Peruvian children with asthma
title_short Association of traffic air pollution and rhinitis quality of life in Peruvian children with asthma
title_sort association of traffic air pollution and rhinitis quality of life in peruvian children with asthma
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862476/
https://www.ncbi.nlm.nih.gov/pubmed/29561906
http://dx.doi.org/10.1371/journal.pone.0193910
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