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Report of a series of 82 cases of Buruli ulcer from Nigeria treated in Benin, from 2006 to 2016

BACKGROUND: Nigeria is one of the countries endemic for Buruli ulcer (BU) in West Africa but did not have a control programme until recently. As a result, BU patients often access treatment services in neighbouring Benin where dedicated health facilities have been established to provide treatment fr...

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Autores principales: Ayelo, Gilbert Adjimon, Anagonou, Esai, Wadagni, Anita Carolle, Barogui, Yves Thierry, Dossou, Ange Dodji, Houezo, Jean Gabin, Aguiar, Julia, Johnson, Roch Christian, Saizonou, Raoul, Asiedu, Kingsley, Sopoh, Ghislain Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862520/
https://www.ncbi.nlm.nih.gov/pubmed/29522516
http://dx.doi.org/10.1371/journal.pntd.0006358
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author Ayelo, Gilbert Adjimon
Anagonou, Esai
Wadagni, Anita Carolle
Barogui, Yves Thierry
Dossou, Ange Dodji
Houezo, Jean Gabin
Aguiar, Julia
Johnson, Roch Christian
Saizonou, Raoul
Asiedu, Kingsley
Sopoh, Ghislain Emmanuel
author_facet Ayelo, Gilbert Adjimon
Anagonou, Esai
Wadagni, Anita Carolle
Barogui, Yves Thierry
Dossou, Ange Dodji
Houezo, Jean Gabin
Aguiar, Julia
Johnson, Roch Christian
Saizonou, Raoul
Asiedu, Kingsley
Sopoh, Ghislain Emmanuel
author_sort Ayelo, Gilbert Adjimon
collection PubMed
description BACKGROUND: Nigeria is one of the countries endemic for Buruli ulcer (BU) in West Africa but did not have a control programme until recently. As a result, BU patients often access treatment services in neighbouring Benin where dedicated health facilities have been established to provide treatment free of charge for BU patients. This study aimed to describe the epidemiological, clinical, biological and therapeutic characteristics of cases from Nigeria treated in three of the four treatment centers in Benin. METHODOLOGY/PRINCIPAL FINDINGS: A series of 82 BU cases from Nigeria were treated in three centres in Benin during 2006–2016 and are retrospectively described. The majority of these patients came from Ogun and Lagos States which border Benin. Most of the cases were diagnosed with ulcerative lesions (80.5%) and WHO category III lesions (82.9%); 97.5% were healed after a median hospital stay of 46 days (interquartile range [IQR]: 32–176 days). CONCLUSIONS/SIGNIFICANCE: This report adds to the epidemiological understanding of BU in Nigeria in the hope that the programme will intensify efforts aimed at early case detection and treatment.
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spelling pubmed-58625202018-03-28 Report of a series of 82 cases of Buruli ulcer from Nigeria treated in Benin, from 2006 to 2016 Ayelo, Gilbert Adjimon Anagonou, Esai Wadagni, Anita Carolle Barogui, Yves Thierry Dossou, Ange Dodji Houezo, Jean Gabin Aguiar, Julia Johnson, Roch Christian Saizonou, Raoul Asiedu, Kingsley Sopoh, Ghislain Emmanuel PLoS Negl Trop Dis Research Article BACKGROUND: Nigeria is one of the countries endemic for Buruli ulcer (BU) in West Africa but did not have a control programme until recently. As a result, BU patients often access treatment services in neighbouring Benin where dedicated health facilities have been established to provide treatment free of charge for BU patients. This study aimed to describe the epidemiological, clinical, biological and therapeutic characteristics of cases from Nigeria treated in three of the four treatment centers in Benin. METHODOLOGY/PRINCIPAL FINDINGS: A series of 82 BU cases from Nigeria were treated in three centres in Benin during 2006–2016 and are retrospectively described. The majority of these patients came from Ogun and Lagos States which border Benin. Most of the cases were diagnosed with ulcerative lesions (80.5%) and WHO category III lesions (82.9%); 97.5% were healed after a median hospital stay of 46 days (interquartile range [IQR]: 32–176 days). CONCLUSIONS/SIGNIFICANCE: This report adds to the epidemiological understanding of BU in Nigeria in the hope that the programme will intensify efforts aimed at early case detection and treatment. Public Library of Science 2018-03-09 /pmc/articles/PMC5862520/ /pubmed/29522516 http://dx.doi.org/10.1371/journal.pntd.0006358 Text en © 2018 Ayelo et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Ayelo, Gilbert Adjimon
Anagonou, Esai
Wadagni, Anita Carolle
Barogui, Yves Thierry
Dossou, Ange Dodji
Houezo, Jean Gabin
Aguiar, Julia
Johnson, Roch Christian
Saizonou, Raoul
Asiedu, Kingsley
Sopoh, Ghislain Emmanuel
Report of a series of 82 cases of Buruli ulcer from Nigeria treated in Benin, from 2006 to 2016
title Report of a series of 82 cases of Buruli ulcer from Nigeria treated in Benin, from 2006 to 2016
title_full Report of a series of 82 cases of Buruli ulcer from Nigeria treated in Benin, from 2006 to 2016
title_fullStr Report of a series of 82 cases of Buruli ulcer from Nigeria treated in Benin, from 2006 to 2016
title_full_unstemmed Report of a series of 82 cases of Buruli ulcer from Nigeria treated in Benin, from 2006 to 2016
title_short Report of a series of 82 cases of Buruli ulcer from Nigeria treated in Benin, from 2006 to 2016
title_sort report of a series of 82 cases of buruli ulcer from nigeria treated in benin, from 2006 to 2016
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862520/
https://www.ncbi.nlm.nih.gov/pubmed/29522516
http://dx.doi.org/10.1371/journal.pntd.0006358
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