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Report of a series of 82 cases of Buruli ulcer from Nigeria treated in Benin, from 2006 to 2016
BACKGROUND: Nigeria is one of the countries endemic for Buruli ulcer (BU) in West Africa but did not have a control programme until recently. As a result, BU patients often access treatment services in neighbouring Benin where dedicated health facilities have been established to provide treatment fr...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862520/ https://www.ncbi.nlm.nih.gov/pubmed/29522516 http://dx.doi.org/10.1371/journal.pntd.0006358 |
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author | Ayelo, Gilbert Adjimon Anagonou, Esai Wadagni, Anita Carolle Barogui, Yves Thierry Dossou, Ange Dodji Houezo, Jean Gabin Aguiar, Julia Johnson, Roch Christian Saizonou, Raoul Asiedu, Kingsley Sopoh, Ghislain Emmanuel |
author_facet | Ayelo, Gilbert Adjimon Anagonou, Esai Wadagni, Anita Carolle Barogui, Yves Thierry Dossou, Ange Dodji Houezo, Jean Gabin Aguiar, Julia Johnson, Roch Christian Saizonou, Raoul Asiedu, Kingsley Sopoh, Ghislain Emmanuel |
author_sort | Ayelo, Gilbert Adjimon |
collection | PubMed |
description | BACKGROUND: Nigeria is one of the countries endemic for Buruli ulcer (BU) in West Africa but did not have a control programme until recently. As a result, BU patients often access treatment services in neighbouring Benin where dedicated health facilities have been established to provide treatment free of charge for BU patients. This study aimed to describe the epidemiological, clinical, biological and therapeutic characteristics of cases from Nigeria treated in three of the four treatment centers in Benin. METHODOLOGY/PRINCIPAL FINDINGS: A series of 82 BU cases from Nigeria were treated in three centres in Benin during 2006–2016 and are retrospectively described. The majority of these patients came from Ogun and Lagos States which border Benin. Most of the cases were diagnosed with ulcerative lesions (80.5%) and WHO category III lesions (82.9%); 97.5% were healed after a median hospital stay of 46 days (interquartile range [IQR]: 32–176 days). CONCLUSIONS/SIGNIFICANCE: This report adds to the epidemiological understanding of BU in Nigeria in the hope that the programme will intensify efforts aimed at early case detection and treatment. |
format | Online Article Text |
id | pubmed-5862520 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-58625202018-03-28 Report of a series of 82 cases of Buruli ulcer from Nigeria treated in Benin, from 2006 to 2016 Ayelo, Gilbert Adjimon Anagonou, Esai Wadagni, Anita Carolle Barogui, Yves Thierry Dossou, Ange Dodji Houezo, Jean Gabin Aguiar, Julia Johnson, Roch Christian Saizonou, Raoul Asiedu, Kingsley Sopoh, Ghislain Emmanuel PLoS Negl Trop Dis Research Article BACKGROUND: Nigeria is one of the countries endemic for Buruli ulcer (BU) in West Africa but did not have a control programme until recently. As a result, BU patients often access treatment services in neighbouring Benin where dedicated health facilities have been established to provide treatment free of charge for BU patients. This study aimed to describe the epidemiological, clinical, biological and therapeutic characteristics of cases from Nigeria treated in three of the four treatment centers in Benin. METHODOLOGY/PRINCIPAL FINDINGS: A series of 82 BU cases from Nigeria were treated in three centres in Benin during 2006–2016 and are retrospectively described. The majority of these patients came from Ogun and Lagos States which border Benin. Most of the cases were diagnosed with ulcerative lesions (80.5%) and WHO category III lesions (82.9%); 97.5% were healed after a median hospital stay of 46 days (interquartile range [IQR]: 32–176 days). CONCLUSIONS/SIGNIFICANCE: This report adds to the epidemiological understanding of BU in Nigeria in the hope that the programme will intensify efforts aimed at early case detection and treatment. Public Library of Science 2018-03-09 /pmc/articles/PMC5862520/ /pubmed/29522516 http://dx.doi.org/10.1371/journal.pntd.0006358 Text en © 2018 Ayelo et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Ayelo, Gilbert Adjimon Anagonou, Esai Wadagni, Anita Carolle Barogui, Yves Thierry Dossou, Ange Dodji Houezo, Jean Gabin Aguiar, Julia Johnson, Roch Christian Saizonou, Raoul Asiedu, Kingsley Sopoh, Ghislain Emmanuel Report of a series of 82 cases of Buruli ulcer from Nigeria treated in Benin, from 2006 to 2016 |
title | Report of a series of 82 cases of Buruli ulcer from Nigeria treated in Benin, from 2006 to 2016 |
title_full | Report of a series of 82 cases of Buruli ulcer from Nigeria treated in Benin, from 2006 to 2016 |
title_fullStr | Report of a series of 82 cases of Buruli ulcer from Nigeria treated in Benin, from 2006 to 2016 |
title_full_unstemmed | Report of a series of 82 cases of Buruli ulcer from Nigeria treated in Benin, from 2006 to 2016 |
title_short | Report of a series of 82 cases of Buruli ulcer from Nigeria treated in Benin, from 2006 to 2016 |
title_sort | report of a series of 82 cases of buruli ulcer from nigeria treated in benin, from 2006 to 2016 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862520/ https://www.ncbi.nlm.nih.gov/pubmed/29522516 http://dx.doi.org/10.1371/journal.pntd.0006358 |
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