Characterization of the rhesus macaque (Macaca mulatta) scrub typhus model: Susceptibility to intradermal challenge with the human pathogen Orientia tsutsugamushi Karp

BACKGROUND: Scrub typhus is an important endemic disease in tropical Asia caused by Orientia tsutsugamushi for which no effective broadly protective vaccine is available. The successful evaluation of vaccine candidates requires well-characterized animal models and a better understanding of the immun...

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Detalles Bibliográficos
Autores principales: Sunyakumthorn, Piyanate, Somponpun, Suwit J., Im-erbsin, Rawiwan, Anantatat, Tippawan, Jenjaroen, Kemajittra, Dunachie, Susanna J., Lombardini, Eric D., Burke, Robin L., Blacksell, Stuart D., Jones, James W., Mason, Carl J., Richards, Allen L., Day, Nicholas P. J., Paris, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862536/
https://www.ncbi.nlm.nih.gov/pubmed/29522521
http://dx.doi.org/10.1371/journal.pntd.0006305

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