Cargando…

EIF3C-enhanced exosome secretion promotes angiogenesis and tumorigenesis of human hepatocellular carcinoma

Targeting tumor angiogenesis is a common strategy against human hepatocellular carcinoma (HCC). However, identification of molecular targets as biomarker for elevating therapeutic efficacy is critical to prolong HCC patient survival. Here, we showed that EIF3C (eukaryotic translation initiation fact...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Hsin-Yi, Chen, Chi-Kuan, Ho, Chun-Ming, Lee, Szu-Shuo, Chang, Chieh-Yu, Chen, Kuan-Ju, Jou, Yuh-Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862571/ https://www.ncbi.nlm.nih.gov/pubmed/29568350 http://dx.doi.org/10.18632/oncotarget.24149

Ejemplares similares

Pyrimidine metabolic rate limiting enzymes in poorly-differentiated hepatocellular carcinoma are signature genes of cancer stemness and associated with poor prognosis
por: Yeh, Hsi-Wen, et al.
Publicado: (2017)

Prognostic comparative genes predict targets for sorafenib combination therapies in hepatocellular carcinoma
por: Ho, Chun-Ming, et al.
Publicado: (2022)

Hepatocellular Carcinoma Cell-Secreted Exosomal MicroRNA-210 Promotes Angiogenesis In Vitro and In Vivo
por: Lin, Xue-Jia, et al.
Publicado: (2018)

Somatic A‐to‐I RNA‐edited RHOA isoform 2 specific‐R176G mutation promotes tumor progression in lung adenocarcinoma
por: Chen, Kuan‐Ju, et al.
Publicado: (2022)

Escape from IFN-γ-dependent immunosurveillance in tumorigenesis
por: Lin, Chiou-Feng, et al.
Publicado: (2017)

Imaging of angiogenesis of human umbilical vein endothelial cells by uptake of exosomes secreted from hepatocellular carcinoma cells
por: Yukawa, Hiroshi, et al.
Publicado: (2018)

Exosomes secreted by chemoresistant ovarian cancer cells promote angiogenesis
por: Li, Zhang, et al.
Publicado: (2021)

Exosomal MiR-199a-5p Inhibits Tumorigenesis and Angiogenesis by Targeting VEGFA in Osteosarcoma
por: Zhang, Lu, et al.
Publicado: (2022)

Exosomes secreted by endothelial progenitor cells accelerate bone regeneration during distraction osteogenesis by stimulating angiogenesis
por: Jia, Yachao, et al.
Publicado: (2019)

Breast Cancer Cells Induce Cancer-Associated Fibroblasts to Secrete Hepatocyte Growth Factor to Enhance Breast Tumorigenesis
por: Tyan, Shiaw-Wei, et al.
Publicado: (2011)

Tumor-associated Exosomes Are Involved in Hepatocellular Carcinoma Tumorigenesis, Diagnosis, and Treatment
por: Wang, Hang, et al.
Publicado: (2022)

Increased Angiogenesis by Exosomes Secreted by Adipose-Derived Stem Cells upon Lipopolysaccharide Stimulation
por: Wu, Shao-Chun, et al.
Publicado: (2021)

Roles of eIF3m in the tumorigenesis of triple negative breast cancer
por: Han, Wei, et al.
Publicado: (2020)

Microbiome dysbiosis inhibits carcinogen-induced murine oral tumorigenesis
por: Chen, Yuh-Ling, et al.
Publicado: (2022)

Xist reduction in breast cancer upregulates AKT phosphorylation via HDAC3-mediated repression of PHLPP1 expression
por: Huang, Yen-Sung, et al.
Publicado: (2016)

Glucose Starvation in Cardiomyocytes Enhances Exosome Secretion and Promotes Angiogenesis in Endothelial Cells
por: Garcia, Nahuel A., et al.
Publicado: (2015)

Ovarian cancer cell-secreted exosomal miR-205 promotes metastasis by inducing angiogenesis
por: He, Liuqing, et al.
Publicado: (2019)

Inhibition of VEGF(165)/VEGFR2-dependent signaling by LECT2 suppresses hepatocellular carcinoma angiogenesis
por: Chen, Chi-Kuan, et al.
Publicado: (2016)

Angiopoietin-2 induces angiogenesis via exosomes in human hepatocellular carcinoma
por: Xie, Ji-yan, et al.
Publicado: (2020)

Patient-Specific Instrument Guided Double Chevron-Cut Distal Femur Osteotomy
por: Huang, Yen-Chun, et al.
Publicado: (2021)

Long noncoding RNA Smyca coactivates TGF-β/Smad and Myc pathways to drive tumor progression
por: Chen, Hsin-Yi, et al.
Publicado: (2022)

Gastric cancer–secreted exosomal X26nt increases angiogenesis and vascular permeability by targeting VE‐cadherin
por: Chen, Xiaocui, et al.
Publicado: (2021)

eIF4E promotes tumorigenesis and modulates chemosensitivity to cisplatin in esophageal squamous cell carcinoma
por: Liu, Ting, et al.
Publicado: (2016)

Exosomal circLPAR1 functions in colorectal cancer diagnosis and tumorigenesis through suppressing BRD4 via METTL3–eIF3h interaction
por: Zheng, Rui, et al.
Publicado: (2022)

LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation
por: Peng, Xueqiang, et al.
Publicado: (2021)

Ibrutinib Inhibits Angiogenesis and Tumorigenesis in a BTK-Independent Manner
por: Liu, Jia, et al.
Publicado: (2022)

Exosomal circCOL1A1 promotes angiogenesis via recruiting EIF4A3 protein and activating Smad2/3 pathway in colorectal cancer
por: Hu, Gui, et al.
Publicado: (2023)

Exosome-transmitted long non-coding RNA SENP3-EIF4A1 suppresses the progression of hepatocellular carcinoma
por: Wang, Jianchu, et al.
Publicado: (2020)

Angiogenesis: Managing the Culprits behind Tumorigenesis and Metastasis
por: Yehya, Ashwaq Hamid Salem, et al.
Publicado: (2018)

Implications of Angiogenesis Involvement in Arthritis
por: MacDonald, Iona J., et al.
Publicado: (2018)

Circ‐SPECC1 modulates TGFβ2 and autophagy under oxidative stress by sponging miR‐33a to promote hepatocellular carcinoma tumorigenesis
por: Zhang, Bin, et al.
Publicado: (2020)

Oxidative stress in retinal pigment epithelium cells increases exosome secretion and promotes angiogenesis in endothelial cells
por: Atienzar‐Aroca, Sandra, et al.
Publicado: (2016)

Nuclear exosome HMGB3 secreted by nasopharyngeal carcinoma cells promotes tumour metastasis by inducing angiogenesis
por: Zhang, Kaiwen, et al.
Publicado: (2021)

FNDC3B promotes cell migration and tumor metastasis in hepatocellular carcinoma
por: Lin, Chin-Hui, et al.
Publicado: (2016)

M2 macrophage-secreted exosomes promote metastasis and increase vascular permeability in hepatocellular carcinoma
por: Lu, Yiwei, et al.
Publicado: (2023)

Macrophage-secreted interleukin-35 regulates cancer cell plasticity to facilitate metastatic colonization
por: Lee, Chih-Chan, et al.
Publicado: (2018)

Exosomal circRNA-100338 promotes hepatocellular carcinoma metastasis via enhancing invasiveness and angiogenesis
por: Huang, Xiu-Yan, et al.
Publicado: (2020)

Exosomal MiR-1290 Promotes Angiogenesis of Hepatocellular Carcinoma via Targeting SMEK1
por: Wang, Qiong, et al.
Publicado: (2021)

WW Domain-Containing Proteins YAP and TAZ in the Hippo Pathway as Key Regulators in Stemness Maintenance, Tissue Homeostasis, and Tumorigenesis
por: Chen, Yu-An, et al.
Publicado: (2019)

The TRPM7 channel reprograms cellular glycolysis to drive tumorigenesis and angiogenesis
por: Wu, Wanzhou, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6cfcknrgame313fhh3c4q4m0j2