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miR-128 inhibits telomerase activity by targeting TERT mRNA
Telomerase is a unique cellular reverse transcriptase (RT) essential for maintaining telomere stability and required for the unlimited proliferation of cancer cells. The limiting determinant of telomerase activity is the catalytic component TERT, and TERT expression is closely correlated with telome...
Autores principales: | Guzman, Herlinda, Sanders, Katie, Idica, Adam, Bochnakian, Aurore, Jury, Douglas, Daugaard, Iben, Zisoulis, Dimitrios G, Pedersen, Irene Munk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862575/ https://www.ncbi.nlm.nih.gov/pubmed/29568354 http://dx.doi.org/10.18632/oncotarget.24284 |
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