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miR-128 inhibits telomerase activity by targeting TERT mRNA

Telomerase is a unique cellular reverse transcriptase (RT) essential for maintaining telomere stability and required for the unlimited proliferation of cancer cells. The limiting determinant of telomerase activity is the catalytic component TERT, and TERT expression is closely correlated with telome...

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Detalles Bibliográficos
Autores principales: Guzman, Herlinda, Sanders, Katie, Idica, Adam, Bochnakian, Aurore, Jury, Douglas, Daugaard, Iben, Zisoulis, Dimitrios G, Pedersen, Irene Munk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862575/
https://www.ncbi.nlm.nih.gov/pubmed/29568354
http://dx.doi.org/10.18632/oncotarget.24284

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