Cargando…

miR-128 inhibits telomerase activity by targeting TERT mRNA

Telomerase is a unique cellular reverse transcriptase (RT) essential for maintaining telomere stability and required for the unlimited proliferation of cancer cells. The limiting determinant of telomerase activity is the catalytic component TERT, and TERT expression is closely correlated with telome...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guzman, Herlinda, Sanders, Katie, Idica, Adam, Bochnakian, Aurore, Jury, Douglas, Daugaard, Iben, Zisoulis, Dimitrios G, Pedersen, Irene Munk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862575/ https://www.ncbi.nlm.nih.gov/pubmed/29568354 http://dx.doi.org/10.18632/oncotarget.24284

Ejemplares similares

miR-128 Restriction of LINE-1 (L1) Retrotransposition Is Dependent on Targeting hnRNPA1 mRNA
por: Fung, Lianna, et al.
Publicado: (2019)

miR-151a enhances Slug dependent angiogenesis
por: Jury, Douglas, et al.
Publicado: (2020)

miR-151a induces partial EMT by regulating E-cadherin in NSCLC cells
por: Daugaard, I, et al.
Publicado: (2017)

TERT Promoter Mutations and Telomerase in Melanoma
por: Guo, Yuchen, et al.
Publicado: (2022)

Alternative Splicing of hTERT Pre-mRNA: A Potential Strategy for the Regulation of Telomerase Activity
por: Liu, Xuewen, et al.
Publicado: (2017)

Regulation and clinical potential of telomerase reverse transcriptase (TERT/hTERT) in breast cancer
por: Yang, Ruozhu, et al.
Publicado: (2023)

Telomere Lengths, Pulmonary Fibrosis and Telomerase (TERT) Mutations
por: Diaz de Leon, Alberto, et al.
Publicado: (2010)

Transcriptional Regulation of Telomerase Reverse Transcriptase (TERT) by MYC
por: Khattar, Ekta, et al.
Publicado: (2017)

Human Telomerase Reverse Transcriptase (hTERT) Q169 Is Essential for Telomerase Function In Vitro and In Vivo
por: Wyatt, Haley D. M., et al.
Publicado: (2009)

P. berghei Telomerase Subunit TERT is Essential for Parasite Survival
por: Religa, Agnieszka A., et al.
Publicado: (2014)

Cancer-associated TERT promoter mutations abrogate telomerase silencing
por: Chiba, Kunitoshi, et al.
Publicado: (2015)

Identification of human TERT elements necessary for telomerase recruitment to telomeres
por: Schmidt, Jens C, et al.
Publicado: (2014)

Telomerase Reverse Transcriptase (TERT) in Action: Cross-Talking with Epigenetics
por: Yuan, Xiaotian, et al.
Publicado: (2019)

Tumor cells derived exosomes contain hTERT mRNA and transform nonmalignant fibroblasts into telomerase positive cells
por: Gutkin, Anna, et al.
Publicado: (2016)

NOVA1 directs PTBP1 to hTERT pre-mRNA and promotes telomerase activity in cancer cells
por: Sayed, Mohammed E., et al.
Publicado: (2018)

mRNA quantification and clinical evaluation of telomerase reverse transcriptase subunit (hTERT) in intracranial tumours of patients in the island of Crete
por: Yannopoulos, A, et al.
Publicado: (2005)

Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours
por: Lantuejoul, S, et al.
Publicado: (2004)

hTERT promotes cell adhesion and migration independent of telomerase activity
por: Liu, Haiying, et al.
Publicado: (2016)

Evolution of TERT-interacting lncRNAs: expanding the regulatory landscape of telomerase
por: Nelson, Andrew D. L., et al.
Publicado: (2015)

PCDH10 Interacts With hTERT and Negatively Regulates Telomerase Activity
por: Zhou, Li-Na, et al.
Publicado: (2015)

Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene
por: Ramlee, Muhammad Khairul, et al.
Publicado: (2016)

Telomerase Reverse Transcriptase (TERT) Regulation in Thyroid Cancer: A Review
por: McKelvey, Brittany A., et al.
Publicado: (2020)

Activating Telomerase TERT Promoter Mutations and Their Application for the Detection of Bladder Cancer
por: Zvereva, Maria, et al.
Publicado: (2020)

New somatic TERT promoter variants enhance the Telomerase activity in Glioblastoma
por: Pierini, Tiziana, et al.
Publicado: (2020)

Nuclear-specific accumulation of telomerase reverse transcriptase (TERT) mRNA in TERT promoter mutated follicular thyroid tumours visualised by in situ hybridisation: a possible clinical screening tool?
por: Hellgren, L Samuel, et al.
Publicado: (2022)

Allele‐specific proximal promoter hypomethylation of the telomerase reverse transcriptase gene (TERT) associates with TERT expression in multiple cancers
por: Rowland, Teisha J., et al.
Publicado: (2020)

The role of telomerase reverse transcriptase (TERT) promoter mutations in prognosis in bladder cancer
por: Wan, Song, et al.
Publicado: (2021)

Effects of hTERT transfection on the telomere and telomerase of Periplaneta americana cells in vitro
por: Ma, Chenjing, et al.
Publicado: (2023)

Reactivation of telomerase reverse transcriptase expression in cancer: the role of TERT promoter mutations
por: Tornesello, Maria Lina, et al.
Publicado: (2023)

Quantitative relationship between functionally active telomerase and major telomerase components (hTERT and hTR) in acute leukaemia cells
por: Ohyashiki, J H, et al.
Publicado: (2005)

The Role of miR-128 in Neurodegenerative Diseases
por: Lanza, Marika, et al.
Publicado: (2023)

Absence of telomerase activity and telomerase catalytic subunit mRNA in melanocyte cultures
por: Dhaene, K, et al.
Publicado: (2000)

Herpesvirus Telomerase RNA(vTR)-Dependent Lymphoma Formation Does Not Require Interaction of vTR with Telomerase Reverse Transcriptase (TERT)
por: Kaufer, Benedikt B., et al.
Publicado: (2010)

Inhibition of Human Telomerase Reverse Transcritpase (hTERT) and Telomerase Activity by Curcumin in Human Mammary Epithelial and Breast Carcinoma Cell Lines
por: Ramachandran, Chappail, et al.
Publicado: (2001)

Many disease-associated variants of hTERT retain high telomerase enzymatic activity
por: Zaug, Arthur J., et al.
Publicado: (2013)

Telomerase Expression by Aberrant Methylation of the TERT Promoter in Melanoma Arising in Giant Congenital Nevi
por: Fan, Yiping, et al.
Publicado: (2016)

Cancer-Specific Telomerase Reverse Transcriptase (TERT) Promoter Mutations: Biological and Clinical Implications
por: Liu, Tiantian, et al.
Publicado: (2016)

Mechanisms of human telomerase reverse transcriptase (hTERT) regulation: clinical impacts in cancer
por: Leão, Ricardo, et al.
Publicado: (2018)

TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter
por: Rajagopalan, Deepa, et al.
Publicado: (2017)

Tianshengyuan-1 (TSY-1) regulates cellular Telomerase activity by methylation of TERT promoter
por: Yu, Weibo, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_k6g93s18fhqtlg5q4fvhronhqa