Persistent DNA strand breaks induce a CAF-like phenotype in normal fibroblasts

Cancer-associated fibroblasts (CAFs) are an emerging target for cancer therapy as they promote tumour growth and metastatic potential. However, CAF targeting is complicated by the lack of knowledge-based strategies aiming to selectively eliminate these cells. There is a growing body of evidence sugg...

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Detalles Bibliográficos
Autores principales: Legrand, Arnaud J., Poletto, Mattia, Pankova, Daniela, Clementi, Elena, Moore, John, Castro-Giner, Francesc, Ryan, Anderson J., O’Neill, Eric, Markkanen, Enni, Dianov, Grigory L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862606/
https://www.ncbi.nlm.nih.gov/pubmed/29568385
http://dx.doi.org/10.18632/oncotarget.24446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862606/
https://www.ncbi.nlm.nih.gov/pubmed/29568385
http://dx.doi.org/10.18632/oncotarget.24446

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