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Correlation of MET gene amplification and TP53 mutation with PD-L1 expression in non-small cell lung cancer

BACKGROUND: The role of MET amplification in lung cancer, particularly in relation to checkpoint inhibition and EGFR WT, has not been fully explored. In this study, we correlated PD-L1 expression with MET amplification and EGFR, KRAS, or TP53 mutation in primary lung cancer. METHODS: In this retrosp...

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Detalles Bibliográficos
Autores principales: Albitar, Maher, Sudarsanam, Sucha, Ma, Wanlong, Jiang, Shiping, Chen, Wayne, Funari, Vincent, Blocker, Forrest, Agersborg, Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862607/
https://www.ncbi.nlm.nih.gov/pubmed/29568386
http://dx.doi.org/10.18632/oncotarget.24455