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The impact of the IGF-1 system of cancer cells on radiation response – An in vitro study

BACKGROUND: Overexpression of the insulin-like growth factor-1 receptor (IGF-1R) is associated with increased cell proliferation, differentiation, transformation, and tumorigenicity. Additionally, signaling involved in the resistance of cancer cells to radiotherapy originates from IGF-1R. The purpos...

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Detalles Bibliográficos
Autores principales: Venkatachalam, Senthiladipan, Mettler, Esther, Fottner, Christian, Miederer, Matthias, Kaina, Bernd, Weber, Matthias M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862664/
https://www.ncbi.nlm.nih.gov/pubmed/29594222
http://dx.doi.org/10.1016/j.ctro.2017.09.006

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