A spliced latency-associated VZV transcript maps antisense to the viral transactivator gene 61

Varicella-zoster virus (VZV), an alphaherpesvirus, establishes lifelong latent infection in the neurons of >90% humans worldwide, reactivating in one-third to cause shingles, debilitating pain and stroke. How VZV maintains latency remains unclear. Here, using ultra-deep virus-enriched RNA sequenc...

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Detalles Bibliográficos
Autores principales: Depledge, Daniel P., Ouwendijk, Werner J. D., Sadaoka, Tomohiko, Braspenning, Shirley E., Mori, Yasuko, Cohrs, Randall J., Verjans, Georges M. G. M., Breuer, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862956/
https://www.ncbi.nlm.nih.gov/pubmed/29563516
http://dx.doi.org/10.1038/s41467-018-03569-2

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