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Identification of potential regulatory mutations using multi-omics analysis and haplotyping of lung adenocarcinoma cell lines

The functional relevancy of mutations occurring in the regulatory regions in cancers remains mostly elusive. Here, we identified and analyzed regulatory mutations having transcriptional consequences in lung adenocarcinoma-derived cell lines. We phased the mutations in the regulatory regions to the d...

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Detalles Bibliográficos
Autores principales: Sereewattanawoot, Sarun, Suzuki, Ayako, Seki, Masahide, Sakamoto, Yoshitaka, Kohno, Takashi, Sugano, Sumio, Tsuchihara, Katsuya, Suzuki, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862974/
https://www.ncbi.nlm.nih.gov/pubmed/29563587
http://dx.doi.org/10.1038/s41598-018-23342-1

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