Haplotype Heritability Mapping Method Uncovers Missing Heritability of Complex Traits

We propose a novel approach to analyze genomic data that incorporates haplotype information for detecting rare variants within a regional heritability mapping framework. The performance of our approach was tested in a simulation study based on human genotypes. The phenotypes were simulated by genera...

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Detalles Bibliográficos
Autores principales: Shirali, Masoud, Knott, Sara A., Pong-Wong, Ricardo, Navarro, Pau, Haley, Chris S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862984/
https://www.ncbi.nlm.nih.gov/pubmed/29563569
http://dx.doi.org/10.1038/s41598-018-23307-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862984/
https://www.ncbi.nlm.nih.gov/pubmed/29563569
http://dx.doi.org/10.1038/s41598-018-23307-4

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