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Haplotype Heritability Mapping Method Uncovers Missing Heritability of Complex Traits
We propose a novel approach to analyze genomic data that incorporates haplotype information for detecting rare variants within a regional heritability mapping framework. The performance of our approach was tested in a simulation study based on human genotypes. The phenotypes were simulated by genera...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862984/ https://www.ncbi.nlm.nih.gov/pubmed/29563569 http://dx.doi.org/10.1038/s41598-018-23307-4 |