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Lactate as a Potential Biomarker of Sepsis in a Rat Cecal Ligation and Puncture Model

We attempted to investigate whether blood lactate is a useful biomarker for sepsis in a rat cecal ligation and puncture (CLP) model. Male Sprague-Dawley rats underwent approximately 75% cecum ligation and two punctures to induce high-grade sepsis. A lactate of 1.64 mmol/L (Youden score of 0.722) was...

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Detalles Bibliográficos
Autores principales:	Zhai, Xiaozhu, Yang, Zhengfei, Zheng, Guanghui, Yu, Tao, Wang, Peng, Liu, Xuefen, Ling, Qin, Jiang, Longyuan, Tang, Wanchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863333/ https://www.ncbi.nlm.nih.gov/pubmed/29706801 http://dx.doi.org/10.1155/2018/8352727

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