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Clinical Evaluation of Role of Dual Antiplatelet Therapy on Bleeding after Dental Extraction

AIMS AND OBJECTIVES: Altered platelet function and increased bleeding time (BT) can occur with antiplatelet therapy. This study was conducted to evaluate the need for stoppage of dual antiplatelet therapy in patients undergoing dental extractions. MATERIALS AND METHODS: One hundred and fifty patient...

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Autores principales: Babaji, Prashant, Rishal, Yousef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863407/
https://www.ncbi.nlm.nih.gov/pubmed/29599582
http://dx.doi.org/10.4103/ccd.ccd_702_17
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author Babaji, Prashant
Rishal, Yousef
author_facet Babaji, Prashant
Rishal, Yousef
author_sort Babaji, Prashant
collection PubMed
description AIMS AND OBJECTIVES: Altered platelet function and increased bleeding time (BT) can occur with antiplatelet therapy. This study was conducted to evaluate the need for stoppage of dual antiplatelet therapy in patients undergoing dental extractions. MATERIALS AND METHODS: One hundred and fifty patients indicated for dental extraction were grouped as Group I: Consisted of 75 patients on dual antiplatelet therapy and Group II: Consisted of 75 patients who have discontinued antiplatelet therapy 1 week before dental extraction. BT of all the participants was recorded before extraction procedures. Under local anesthesia, single molar tooth indicated for simple extraction was done in both the groups. Suturing along with pressure pack was done after extraction. BT after extraction was statistically checked between the groups after 1 h and 24 h using Chi-square test with P < 0.05. RESULTS: Postoperatively, none of the patients in both the groups showed active bleeding 1 h and 24 h. No bleeding was seen in 73 patients in Group I and 78 patients in Group II after 24 h. CONCLUSION: This study concluded that there is no significant difference in BT in both the groups. Antiplatelet monotherapy or even antiplatelet dual therapy needs no alteration or stopped before minor oral surgical procedures. Most of the postoperative bleeding can be easily controlled by local hemostatic measures.
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spelling pubmed-58634072018-03-29 Clinical Evaluation of Role of Dual Antiplatelet Therapy on Bleeding after Dental Extraction Babaji, Prashant Rishal, Yousef Contemp Clin Dent Original Article AIMS AND OBJECTIVES: Altered platelet function and increased bleeding time (BT) can occur with antiplatelet therapy. This study was conducted to evaluate the need for stoppage of dual antiplatelet therapy in patients undergoing dental extractions. MATERIALS AND METHODS: One hundred and fifty patients indicated for dental extraction were grouped as Group I: Consisted of 75 patients on dual antiplatelet therapy and Group II: Consisted of 75 patients who have discontinued antiplatelet therapy 1 week before dental extraction. BT of all the participants was recorded before extraction procedures. Under local anesthesia, single molar tooth indicated for simple extraction was done in both the groups. Suturing along with pressure pack was done after extraction. BT after extraction was statistically checked between the groups after 1 h and 24 h using Chi-square test with P < 0.05. RESULTS: Postoperatively, none of the patients in both the groups showed active bleeding 1 h and 24 h. No bleeding was seen in 73 patients in Group I and 78 patients in Group II after 24 h. CONCLUSION: This study concluded that there is no significant difference in BT in both the groups. Antiplatelet monotherapy or even antiplatelet dual therapy needs no alteration or stopped before minor oral surgical procedures. Most of the postoperative bleeding can be easily controlled by local hemostatic measures. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5863407/ /pubmed/29599582 http://dx.doi.org/10.4103/ccd.ccd_702_17 Text en Copyright: © 2018 Contemporary Clinical Dentistry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Babaji, Prashant
Rishal, Yousef
Clinical Evaluation of Role of Dual Antiplatelet Therapy on Bleeding after Dental Extraction
title Clinical Evaluation of Role of Dual Antiplatelet Therapy on Bleeding after Dental Extraction
title_full Clinical Evaluation of Role of Dual Antiplatelet Therapy on Bleeding after Dental Extraction
title_fullStr Clinical Evaluation of Role of Dual Antiplatelet Therapy on Bleeding after Dental Extraction
title_full_unstemmed Clinical Evaluation of Role of Dual Antiplatelet Therapy on Bleeding after Dental Extraction
title_short Clinical Evaluation of Role of Dual Antiplatelet Therapy on Bleeding after Dental Extraction
title_sort clinical evaluation of role of dual antiplatelet therapy on bleeding after dental extraction
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863407/
https://www.ncbi.nlm.nih.gov/pubmed/29599582
http://dx.doi.org/10.4103/ccd.ccd_702_17
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