Application of next-generation sequencing to characterize novel mutations in clarithromycin-susceptible Helicobacter pylori strains with A2143G of 23S rRNA gene

BACKGROUND: Clarithromycin (CLR) resistance has become a predominant factor for treatment failure of Helicobacter pylori eradication. Although the molecular mechanism of CLR resistance has been clearly understood in H. pylori, it is lack of evidence of other genes involved in drug resistance. Furthe...

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Detalles Bibliográficos
Autores principales: Chen, Jiaoe, Ye, Liping, Jin, Liangmin, Xu, Xuehua, Xu, Peisong, Wang, Xianjun, Li, Hongzhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863438/
https://www.ncbi.nlm.nih.gov/pubmed/29562911
http://dx.doi.org/10.1186/s12941-018-0259-8

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