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Effective osimertinib treatment in a patient with discordant T790 M mutation detection between liquid biopsy and tissue biopsy

BACKGROUND: We report the successful treatment of the patient with osimertinib 80 mg/day following disease progression and a discordance in the detection of a mechanism of resistance epithelial growth factor receptor (EGFR) T790 M between liquid biopsy and tissue biopsy methods. CASE PRESENTATION: A...

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Detalles Bibliográficos
Autores principales: Mambetsariev, Isa, Vora, Lalit, Yu, Kim Wai, Salgia, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863467/
https://www.ncbi.nlm.nih.gov/pubmed/29562902
http://dx.doi.org/10.1186/s12885-018-4222-z