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Interplay Between Capsule Expression and Uracil Metabolism in Streptococcus pneumoniae D39

Pyrimidine nucleotides play an important role in the biosynthesis of activated nucleotide sugars (NDP-sugars). NDP-sugars are the precursors of structural polysaccharides in bacteria, including capsule, which is a major virulence factor of the human pathogen S. pneumoniae. In this work, we identifie...

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Detalles Bibliográficos
Autores principales:	Carvalho, Sandra M., Kloosterman, Tomas G., Manzoor, Irfan, Caldas, José, Vinga, Susana, Martinussen, Jan, Saraiva, Lígia M., Kuipers, Oscar P., Neves, Ana R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863508/ https://www.ncbi.nlm.nih.gov/pubmed/29599757 http://dx.doi.org/10.3389/fmicb.2018.00321

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