Cargando…

Emergence of CD4+ and CD8+ Polyfunctional T Cell Responses Against Immunodominant Lytic and Latent EBV Antigens in Children With Primary EBV Infection

Long term carriers were shown to generate robust polyfunctional T cell (PFC) responses against lytic and latent antigens of Epstein-Barr virus (EBV). However, the time of emergence of PFC responses against EBV antigens, pattern of immunodominance and difference between CD4+ and CD8+ T cell responses...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lam, Janice K. P., Hui, K. F., Ning, Raymond J., Xu, X. Q., Chan, K. H., Chiang, Alan K. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863510/ https://www.ncbi.nlm.nih.gov/pubmed/29599759 http://dx.doi.org/10.3389/fmicb.2018.00416

Ejemplares similares

The impact of HLA class I and EBV latency‐II antigen‐specific CD8(+) T cells on the pathogenesis of EBV(+) Hodgkin lymphoma
por: Jones, K., et al.
Publicado: (2015)

Curcuminoids as EBV Lytic Activators for Adjuvant Treatment in EBV-Positive Carcinomas
por: Ramayanti, Octavia, et al.
Publicado: (2018)

Identification of Novel Small Organic Compounds with Diverse Structures for the Induction of Epstein-Barr Virus (EBV) Lytic Cycle in EBV-Positive Epithelial Malignancies
por: Choi, Chung King, et al.
Publicado: (2015)

CD8(+) immunodominance among Epstein-Barr virus lytic cycle antigens directly reflects the efficiency of antigen presentation in lytically infected cells
por: Pudney, Victoria A., et al.
Publicado: (2005)

GMP development and preclinical validation of CAR-T cells targeting a lytic EBV antigen for therapy of EBV-associated malignancies
por: Zhang, Xi, et al.
Publicado: (2023)

Contribution of the KSHV and EBV lytic cycles to tumourigenesis
por: Manners, Oliver, et al.
Publicado: (2018)

Adenosine Induces EBV Lytic Reactivation through ADORA1 in EBV-Associated Gastric Carcinoma
por: Choi, Su Jin, et al.
Publicado: (2019)

Cross talk between EBV and telomerase: the role of TERT and NOTCH2 in the switch of latent/lytic cycle of the virus
por: Giunco, S, et al.
Publicado: (2015)

EBV Promotes Human CD8(+) NKT Cell Development
por: Yuling, He, et al.
Publicado: (2010)

CDR3α drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection
por: Kamga, Larisa, et al.
Publicado: (2019)

Adoptive Transfer of EBV Specific CD8(+) T Cell Clones Can Transiently Control EBV Infection in Humanized Mice
por: Antsiferova, Olga, et al.
Publicado: (2014)

Inhibition of autophagy in EBV-positive Burkitt's lymphoma cells enhances EBV lytic genes expression and replication
por: De Leo, A, et al.
Publicado: (2015)

Latent Membrane Protein LMP2A Impairs Recognition of EBV-Infected Cells by CD8+ T Cells
por: Rancan, Chiara, et al.
Publicado: (2015)

Conquering the Nuclear Envelope Barriers by EBV Lytic Replication
por: Lee, Chung-Pei, et al.
Publicado: (2021)

Retraction: EBV Promotes Human CD8(+) NKT Cell Development
por: Yuling, He, et al.
Publicado: (2010)

Immunodominant HIV-1-specific HLA-B- and HLA-C-restricted CD8+ T cells do not differ in polyfunctionality
por: Mkhwanazi, Nompumelelo, et al.
Publicado: (2010)

Polyfunctional CD4(+) T Cell Responses to Immunodominant Epitopes Correlate with Disease Activity of Virulent Salmonella
por: Maybeno, Matt, et al.
Publicado: (2012)

Partial absence of PD‐1 expression by tumor‐infiltrating EBV‐specific CD8(+) T cells in EBV‐driven lymphoepithelioma‐like carcinoma
por: Simoni, Yannick, et al.
Publicado: (2020)

Epstein–Barr Virus (EBV) Rta-Mediated EBV and Kaposi's Sarcoma-Associated Herpesvirus Lytic Reactivations in 293 Cells
por: Chen, Yen-Ju, et al.
Publicado: (2011)

Establishment of Epstein–Barr Virus (EBV) Latent Gene-Expressing T-Cell Lines with an Expression Vector Harboring EBV Nuclear Antigen 1
por: Kanno, Hiroyuki, et al.
Publicado: (2023)

Persistence of EBV Antigen-Specific CD8 T Cell Clonotypes during Homeostatic Immune Reconstitution in Cancer Patients
por: Iancu, Emanuela M., et al.
Publicado: (2013)

Immunodominance of Lytic Cycle Antigens in Epstein-Barr Virus-Specific CD4+ T Cell Preparations for Therapy
por: Adhikary, Dinesh, et al.
Publicado: (2007)

Comprehensive definition of human immunodominant CD8 antigens in tuberculosis
por: Lewinsohn, Deborah A., et al.
Publicado: (2017)

Updates on Epstein–Barr Virus (EBV)-Associated Nasopharyngeal Carcinoma: Emphasis on the Latent Gene Products of EBV
por: Ahmed, Naveed, et al.
Publicado: (2022)

Cytotoxic CD4+ T-cells specific for EBV capsid antigen BORF1 are maintained in long-term latently infected healthy donors
por: Dowell, Alexander C., et al.
Publicado: (2021)

Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy
por: Granato, Marisa, et al.
Publicado: (2017)

Clonal CD8+ T Lymphocytic Proliferation and Karyotypical Abnormalities in an EBV Associated Hemophagocytic Lymphohistiocytosis
por: Zhou, Jiehao, et al.
Publicado: (2015)

Age and CMV-Infection Jointly Affect the EBV-Specific CD8(+) T-Cell Repertoire
por: Lanfermeijer, Josien, et al.
Publicado: (2021)

Concomitant Cytotoxic Effector Differentiation of CD4(+) and CD8(+) T Cells in Response to EBV-Infected B Cells
por: Tamura, Yumi, et al.
Publicado: (2022)

Intracellular Iron Chelation by a Novel Compound, C7, Reactivates Epstein–Barr Virus (EBV) Lytic Cycle via the ERK-Autophagy Axis in EBV-Positive Epithelial Cancers
por: Yiu, Stephanie Pei Tung, et al.
Publicado: (2018)

Immunodominant Tuberculosis CD8 Antigens Preferentially Restricted by HLA-B
por: Lewinsohn, Deborah A, et al.
Publicado: (2007)

Progress in Prophylactic and Therapeutic EBV Vaccine Development Based on Molecular Characteristics of EBV Target Antigens
por: Rozman, Marija, et al.
Publicado: (2022)

CMV Latent Infection Improves CD8+ T Response to SEB Due to Expansion of Polyfunctional CD57+ Cells in Young Individuals
por: Pera, Alejandra, et al.
Publicado: (2014)

C/EBPbeta mediates bortezomib-induced EBV and KSHV lytic gene expression
por: O’Farrell, Courtney, et al.
Publicado: (2010)

Polyfunctional response by ImmTAC (IMCgp100) redirected CD8(+) and CD4(+) T cells
por: Boudousquie, Caroline, et al.
Publicado: (2017)

The EBV Latent Antigen 3C Inhibits Apoptosis through Targeted Regulation of Interferon Regulatory Factors 4 and 8
por: Banerjee, Shuvomoy, et al.
Publicado: (2013)

Proteome-wide analysis of CD8+ T cell responses to EBV reveals differences between primary and persistent infection
por: Forrest, Calum, et al.
Publicado: (2018)

Maintenance of the EBV-specific CD8(+) TCRαβ repertoire in immunosuppressed lung transplant recipients
por: Nguyen, Thi HO, et al.
Publicado: (2017)

CD8 encephalitis with CSF EBV viraemia and HIV drug resistance, a case series
por: Kerr, C., et al.
Publicado: (2020)

Burkitt's lymphoma: differential killing of Epstein-Barr virus (EBV) (+) and EBV(-) Burkitt lymphoma cells in vitro and dose-dependent lytic induction by bortezomib in vivo
por: Dufresne, AL, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_vg0t29tmq8jqr1aijfj5sesgm6