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Oral bioavailability enhancement of agomelatine by loading into nanostructured lipid carriers: Peyer’s patch targeting approach
Agomelatine (AGM) is a new antidepressant drug with a novel mechanism of action and fewer side effects compared with older antidepressants. AGM is a melatonin receptor (MT1 and MT2) agonist and 5-hydroxytryptamine receptor (5-HT(2C)) antagonist. In the present study, the enhancement of the oral bioa...
Autores principales: | Prajapati, Jagruti B, Verma, Sneha D, Patel, Amit A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863623/ https://www.ncbi.nlm.nih.gov/pubmed/29593392 http://dx.doi.org/10.2147/IJN.S124703 |
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