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Curcumin Ag nanoconjugates for improved therapeutic effects in cancer

Curcumin has a broad spectrum of pharmacological activities, one of them is anticancer activity that is mediated through multiple mechanisms. The major disadvantage associated with the use of curcumin is its low bioavailability due to its poor aqueous solubility. Nanoformulations of curcumin provide...

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Detalles Bibliográficos
Autores principales: Shah, Darshini, Savaliya, Reema, Patel, Pal, Kansara, Krupa, Pandya, Alok, Dhawan, Alok, Singh, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863647/
https://www.ncbi.nlm.nih.gov/pubmed/29593400
http://dx.doi.org/10.2147/IJN.S124696
Descripción
Sumario:Curcumin has a broad spectrum of pharmacological activities, one of them is anticancer activity that is mediated through multiple mechanisms. The major disadvantage associated with the use of curcumin is its low bioavailability due to its poor aqueous solubility. Nanoformulations of curcumin provide an effective solution for this problem. In this study, we have synthesized curcumin Ag nanoconjugates and evaluated their anticancer potential.