Curcumin Ag nanoconjugates for improved therapeutic effects in cancer

Curcumin has a broad spectrum of pharmacological activities, one of them is anticancer activity that is mediated through multiple mechanisms. The major disadvantage associated with the use of curcumin is its low bioavailability due to its poor aqueous solubility. Nanoformulations of curcumin provide...

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Detalles Bibliográficos
Autores principales: Shah, Darshini, Savaliya, Reema, Patel, Pal, Kansara, Krupa, Pandya, Alok, Dhawan, Alok, Singh, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863647/
https://www.ncbi.nlm.nih.gov/pubmed/29593400
http://dx.doi.org/10.2147/IJN.S124696
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author Shah, Darshini
Savaliya, Reema
Patel, Pal
Kansara, Krupa
Pandya, Alok
Dhawan, Alok
Singh, Sanjay
author_facet Shah, Darshini
Savaliya, Reema
Patel, Pal
Kansara, Krupa
Pandya, Alok
Dhawan, Alok
Singh, Sanjay
author_sort Shah, Darshini
collection PubMed
description Curcumin has a broad spectrum of pharmacological activities, one of them is anticancer activity that is mediated through multiple mechanisms. The major disadvantage associated with the use of curcumin is its low bioavailability due to its poor aqueous solubility. Nanoformulations of curcumin provide an effective solution for this problem. In this study, we have synthesized curcumin Ag nanoconjugates and evaluated their anticancer potential.
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spelling pubmed-58636472018-03-28 Curcumin Ag nanoconjugates for improved therapeutic effects in cancer Shah, Darshini Savaliya, Reema Patel, Pal Kansara, Krupa Pandya, Alok Dhawan, Alok Singh, Sanjay Int J Nanomedicine Short Report Curcumin has a broad spectrum of pharmacological activities, one of them is anticancer activity that is mediated through multiple mechanisms. The major disadvantage associated with the use of curcumin is its low bioavailability due to its poor aqueous solubility. Nanoformulations of curcumin provide an effective solution for this problem. In this study, we have synthesized curcumin Ag nanoconjugates and evaluated their anticancer potential. Dove Medical Press 2018-03-15 /pmc/articles/PMC5863647/ /pubmed/29593400 http://dx.doi.org/10.2147/IJN.S124696 Text en © 2018 Shah et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Short Report
Shah, Darshini
Savaliya, Reema
Patel, Pal
Kansara, Krupa
Pandya, Alok
Dhawan, Alok
Singh, Sanjay
Curcumin Ag nanoconjugates for improved therapeutic effects in cancer
title Curcumin Ag nanoconjugates for improved therapeutic effects in cancer
title_full Curcumin Ag nanoconjugates for improved therapeutic effects in cancer
title_fullStr Curcumin Ag nanoconjugates for improved therapeutic effects in cancer
title_full_unstemmed Curcumin Ag nanoconjugates for improved therapeutic effects in cancer
title_short Curcumin Ag nanoconjugates for improved therapeutic effects in cancer
title_sort curcumin ag nanoconjugates for improved therapeutic effects in cancer
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863647/
https://www.ncbi.nlm.nih.gov/pubmed/29593400
http://dx.doi.org/10.2147/IJN.S124696
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