Antibodies against chemokine receptors CXCR3 and CXCR4 predict progressive deterioration of lung function in patients with systemic sclerosis

BACKGROUND: The chemokine receptors CXCR3 and CXCR4 are involved in the pathogenesis of fibrosis, a key feature of systemic sclerosis (SSc). It is hypothesized that immunoglobulin (Ig)G antibodies (abs) against these two receptors are present in patients with SSc and are associated with clinical fin...

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Detalles Bibliográficos
Autores principales: Weigold, Florian, Günther, Jeannine, Pfeiffenberger, Moritz, Cabral-Marques, Otavio, Siegert, Elise, Dragun, Duska, Philippe, Aurélie, Regensburger, Ann-Katrin, Recke, Andreas, Yu, Xinhua, Petersen, Frank, Catar, Rusan, Biesen, Robert, Hiepe, Falk, Burmester, Gerd R., Heidecke, Harald, Riemekasten, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863842/
https://www.ncbi.nlm.nih.gov/pubmed/29566745
http://dx.doi.org/10.1186/s13075-018-1545-8

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