Cargando…
Targeting Histone Demethylase LSD1/KDM1a in Neurodegenerative Diseases
The autophagy-lysosome pathway sustains cellular homeostasis and is a protective mechanism against neurodegenerative diseases. Recent findings highlight the role of the histone demethylases LSD1/LDM1A as a pivotal regulator of autophagy process, by controlling the mTORC1 cascade, in neuroblastoma ce...
Autores principales: | Ambrosio, Susanna, Majello, Barbara |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863861/ https://www.ncbi.nlm.nih.gov/pubmed/29581704 http://dx.doi.org/10.1177/1179069518765743 |
Ejemplares similares
-
Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively repress tumor suppressor genes in neuroblastoma
por: Amente, Stefano, et al.
Publicado: (2015) -
Expanding the Role of the Histone Lysine-Specific Demethylase LSD1 in Cancer
por: Majello, Barbara, et al.
Publicado: (2019) -
The histone demethylase LSD1/KDM1A promotes the DNA damage response
por: Mosammaparast, Nima, et al.
Publicado: (2013) -
Extra Virgin Olive Oil Contains a Phenolic Inhibitor of the Histone Demethylase LSD1/KDM1A
por: Cuyàs, Elisabet, et al.
Publicado: (2019) -
Lysine-specific demethylase LSD1 regulates autophagy in neuroblastoma through SESN2-dependent pathway
por: Ambrosio, S, et al.
Publicado: (2017)