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MERS-CoV pathogenesis and antiviral efficacy of licensed drugs in human monocyte-derived antigen-presenting cells

Middle East respiratory syndrome coronavirus (MERS-CoV) presents an emerging threat to public health worldwide by causing severe respiratory disease in humans with high virulence and case fatality rate (about 35%) since 2012. Little is known about the pathogenesis and innate antiviral response in pr...

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Detalles Bibliográficos
Autores principales: Cong, Yu, Hart, Brit J., Gross, Robin, Zhou, Huanying, Frieman, Matthew, Bollinger, Laura, Wada, Jiro, Hensley, Lisa E., Jahrling, Peter B., Dyall, Julie, Holbrook, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864050/
https://www.ncbi.nlm.nih.gov/pubmed/29566060
http://dx.doi.org/10.1371/journal.pone.0194868