Testing therapeutics in cell-based assays: Factors that influence the apparent potency of drugs

Identifying effective antivirals for treating Ebola virus disease (EVD) and minimizing transmission of such disease is critical. A variety of cell-based assays have been developed for evaluating compounds for activity against Ebola virus. However, very few reports discuss the variable assay conditio...

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Detalles Bibliográficos
Autores principales: Postnikova, Elena, Cong, Yu, DeWald, Lisa Evans, Dyall, Julie, Yu, Shuiqing, Hart, Brit J., Zhou, Huanying, Gross, Robin, Logue, James, Cai, Yingyun, Deiuliis, Nicole, Michelotti, Julia, Honko, Anna N., Bennett, Richard S., Holbrook, Michael R., Olinger, Gene G., Hensley, Lisa E., Jahrling, Peter B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864066/
https://www.ncbi.nlm.nih.gov/pubmed/29566079
http://dx.doi.org/10.1371/journal.pone.0194880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864066/
https://www.ncbi.nlm.nih.gov/pubmed/29566079
http://dx.doi.org/10.1371/journal.pone.0194880

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