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Closely related, yet unique: Distinct homo- and heterodimerization patterns of G protein coupled chemokine receptors and their fine-tuning by cholesterol

Chemokine receptors, a subclass of G protein coupled receptors (GPCRs), play essential roles in the human immune system, they are involved in cancer metastasis as well as in HIV-infection. A plethora of studies show that homo- and heterodimers or even higher order oligomers of the chemokine receptor...

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Detalles Bibliográficos
Autores principales: Gahbauer, Stefan, Pluhackova, Kristyna, Böckmann, Rainer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864085/
https://www.ncbi.nlm.nih.gov/pubmed/29529028
http://dx.doi.org/10.1371/journal.pcbi.1006062

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