Cargando…

Argonaute2 and LaminB modulate gene expression by controlling chromatin topology

Drosophila Argonaute2 (AGO2) has been shown to regulate expression of certain loci in an RNA interference (RNAi)-independent manner, but its genome-wide function on chromatin remains unknown. Here, we identified the nuclear scaffolding protein LaminB as a novel interactor of AGO2. When either AGO2 o...

Descripción completa

Detalles Bibliográficos
Autores principales: Nazer, Ezequiel, Dale, Ryan K., Chinen, Madoka, Radmanesh, Behram, Lei, Elissa P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864089/
https://www.ncbi.nlm.nih.gov/pubmed/29529026
http://dx.doi.org/10.1371/journal.pgen.1007276