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Argonaute2 and LaminB modulate gene expression by controlling chromatin topology
Drosophila Argonaute2 (AGO2) has been shown to regulate expression of certain loci in an RNA interference (RNAi)-independent manner, but its genome-wide function on chromatin remains unknown. Here, we identified the nuclear scaffolding protein LaminB as a novel interactor of AGO2. When either AGO2 o...
Autores principales: | Nazer, Ezequiel, Dale, Ryan K., Chinen, Madoka, Radmanesh, Behram, Lei, Elissa P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864089/ https://www.ncbi.nlm.nih.gov/pubmed/29529026 http://dx.doi.org/10.1371/journal.pgen.1007276 |
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