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Development of Tizanidine HCl-Meloxicam loaded mucoadhesive buccal films: In-vitro and in-vivo evaluation

The purpose of the study was to develop Tizanidine HCl (TZN) and Meloxicam (MLX) loaded bilayer mucoadhesive films intended for buccal administration, aiming to enhance the bioavailability. Bilayer films were prepared by solvent evaporation technique selecting arabinoxylan (ARX) as a sustained relea...

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Detalles Bibliográficos
Autores principales: Zaman, Muhammad, Hanif, Muhammad, Shaheryar, Zaib Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864138/
https://www.ncbi.nlm.nih.gov/pubmed/29566073
http://dx.doi.org/10.1371/journal.pone.0194410