APP upregulation contributes to retinal ganglion cell degeneration via JNK3

Axonal injury is a common feature of central nervous system insults. Upregulation of amyloid precursor protein (APP) is observed following central nervous system neurotrauma and is regarded as a marker of central nervous system axonal injury. However, the underlying mechanism by which APP mediates n...

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Detalles Bibliográficos
Autores principales: Liu, Chao, Zhang, Cheng-Wu, Zhou, Yi, Wong, Wan Qing, Lee, Liying Corinne, Ong, Wei Yi, Yoon, Sung Ok, Hong, Wanjin, Fu, Xin-Yuan, Soong, Tuck Wah, Koo, Edward H., Stanton, Lawrence W., Lim, Kah-Leong, Xiao, Zhi-Cheng, Dawe, Gavin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864187/
https://www.ncbi.nlm.nih.gov/pubmed/29238071
http://dx.doi.org/10.1038/s41418-017-0005-3

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