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Autoimmune hemolytic anemia associated with infliximab infusion in ulcerative colitis

Infliximab is a monoclonal antibody that antagonizes the activity of tumor necrosis factor alpha to induce and maintain remission in patients with inflammatory bowel disease. Adverse effects associated with Infliximab infusions include infusion reactions, risk of infections, development of hematolog...

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Detalles Bibliográficos
Autores principales: Mir, Fazia A., Juboori, Alhareth Al, Bragg, Jack D., Tahan, Veysel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kare Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864712/
https://www.ncbi.nlm.nih.gov/pubmed/29607436
http://dx.doi.org/10.14744/nci.2017.77045
Descripción
Sumario:Infliximab is a monoclonal antibody that antagonizes the activity of tumor necrosis factor alpha to induce and maintain remission in patients with inflammatory bowel disease. Adverse effects associated with Infliximab infusions include infusion reactions, risk of infections, development of hematological malignancies, and pancytopenia. Autoimmune hemolytic anemia has rarely been reported in ulcerative colitis. Herein we report a case of drug-induced hemolytic anemia after infliximab infusion for treating ulcerative colitis.