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Asymmetric synthesis of γ-branched amines via rhodium-catalyzed reductive amination
Amines bearing γ-stereocenters are highly important structural motifs in many biologically active compounds. However, reported enantioselective syntheses of these molecules are indirect and often require multiple steps. Herein, we report a general asymmetric route for the one-pot synthesis of chiral...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864842/ https://www.ncbi.nlm.nih.gov/pubmed/29567989 http://dx.doi.org/10.1038/s41467-018-03535-y |