Cargando…

Drug Repositioning in Glioblastoma: A Pathway Perspective

Glioblastoma multiforme (GBM) is the most malignant primary adult brain tumor. The current standard of care is surgical resection, radiation, and chemotherapy treatment, which extends life in most cases. Unfortunately, tumor recurrence is nearly universal and patients with recurrent glioblastoma typ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tan, Sze Kiat, Jermakowicz, Anna, Mookhtiar, Adnan K., Nemeroff, Charles B., Schürer, Stephan C., Ayad, Nagi G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864870/ https://www.ncbi.nlm.nih.gov/pubmed/29615902 http://dx.doi.org/10.3389/fphar.2018.00218

Ejemplares similares

BSCI-23 ANEUPLOIDY PROFILING IN GLIOBLASTOMA IDENTIFIES MECHANISMS OF DISEASE PROGRESSION AND TREATMENT VULNERABILITIES
por: Jermakowicz, Anna, et al.
Publicado: (2022)

Editorial: Drug Repositioning: Current Advances and Future Perspectives
por: Nishimura, Yuhei, et al.
Publicado: (2018)

337 Targeting metabolic and epigenetic programs to re-sensitize glioblastoma to chemotherapy
por: Rowland, Emma, et al.
Publicado: (2023)

MDB-38. COMPUTATIONAL DRUG SENSITIVITY PREDICTS MEDULLOBLASTOMA SUBGROUP-SPECIFIC THERAPEUTICS
por: Jermakowicz, Anna, et al.
Publicado: (2023)

Pathway-Based Drug Repositioning for Breast Cancer Molecular Subtypes
por: Mejía-Pedroza, Raúl A., et al.
Publicado: (2018)

Overcoming Obstacles to Drug Repositioning in Japan
por: Nishimura, Yuhei, et al.
Publicado: (2017)

Drug repositioning: A bibliometric analysis
por: Sun, Guojun, et al.
Publicado: (2022)

Enhancing the Promise of Drug Repositioning through Genetics
por: Pritchard, Jayne-Louise E., et al.
Publicado: (2017)

Repositioning of Hypoglycemic Drug Linagliptin for Cancer Treatment
por: Li, Yong, et al.
Publicado: (2020)

Editorial: Pharmacovigilance and drug repositioning research using pharmacoepidemiology
por: Noguchi, Yoshihiro, et al.
Publicado: (2023)

Drug and disease signature integration identifies synergistic combinations in glioblastoma
por: Stathias, Vasileios, et al.
Publicado: (2018)

Serum long noncoding RNA HOTAIR as a novel diagnostic and prognostic biomarker in glioblastoma multiforme
por: Tan, Sze Kiat, et al.
Publicado: (2018)

The novel BET inhibitor UM-002 reduces glioblastoma cell proliferation and invasion
por: Jermakowicz, Anna M., et al.
Publicado: (2021)

Drug Repositioning in the Mirror of Patenting: Surveying and Mining Uncharted Territory
por: Mucke, Hermann A. M.
Publicado: (2017)

Drug-Repositioning Approaches Based on Medical and Life Science Databases
por: Zamami, Yoshito, et al.
Publicado: (2021)

Unraveling Gene Fusions for Drug Repositioning in High-Risk Neuroblastoma
por: Liu, Zhichao, et al.
Publicado: (2021)

Lung adenocarcinoma-related target gene prediction and drug repositioning
por: Huang, Rui Xuan, et al.
Publicado: (2022)

Drug repositioning based on heterogeneous networks and variational graph autoencoders
por: Lei, Song, et al.
Publicado: (2022)

Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning
por: Langhans, Sigrid A.
Publicado: (2018)

Drug Repositioning with GraphSAGE and Clustering Constraints Based on Drug and Disease Networks
por: Zhang, Yuchen, et al.
Publicado: (2022)

Drug Screening and Drug Repositioning as Promising Therapeutic Approaches for Spinal Muscular Atrophy Treatment
por: Menduti, Giovanna, et al.
Publicado: (2020)

A Proteotranscriptomic-Based Computational Drug-Repositioning Method for Alzheimer’s Disease
por: Lee, Soo Youn, et al.
Publicado: (2020)

Computational Drug Repositioning and Experimental Validation of Ivermectin in Treatment of Gastric Cancer
por: Rabben, Hanne-Line, et al.
Publicado: (2021)

Repositioning of Anti-Inflammatory Drugs for the Treatment of Cervical Cancer Sub-Types
por: Kori, Medi, et al.
Publicado: (2022)

Therapeutic drug repositioning with special emphasis on neurodegenerative diseases: Threats and issues
por: Kakoti, Bibhuti Bhusan, et al.
Publicado: (2022)

Drug Repositioning of Proton Pump Inhibitors for Enhanced Efficacy and Safety of Cancer Chemotherapy
por: Ikemura, Kenji, et al.
Publicado: (2017)

Simvastatin Therapy for Drug Repositioning to Reduce the Risk of Prostate Cancer Mortality in Patients With Hyperlipidemia
por: Chen, Yu-An, et al.
Publicado: (2018)

Master Regulators Connectivity Map: A Transcription Factors-Centered Approach to Drug Repositioning
por: De Bastiani, Marco A., et al.
Publicado: (2018)

Drug Repositioning for Noonan and LEOPARD Syndromes by Integrating Transcriptomics With a Structure-Based Approach
por: Zhu, Liyuan, et al.
Publicado: (2020)

Advances in the treatment of autosomal recessive congenital ichthyosis, a look towards the repositioning of drugs
por: Peña-Corona, Sheila I., et al.
Publicado: (2023)

Organoid Models of Glioblastoma and Their Role in Drug Discovery
por: Rybin, Matthew J., et al.
Publicado: (2021)

Computational drug repositioning for peripheral arterial disease: prediction of anti-inflammatory and pro-angiogenic therapeutics
por: Chu, Liang-Hui, et al.
Publicado: (2015)

Repositioning an Immunomodulatory Drug Vidofludimus as a Farnesoid X Receptor Modulator With Therapeutic Effects on NAFLD
por: Zhu, Yanlin, et al.
Publicado: (2020)

Immunotherapy and Epigenetic Pathway Modulation in Glioblastoma Multiforme
por: Chin, Christopher, et al.
Publicado: (2018)

Virtual screening and drug repositioning of FDA-approved drugs from the ZINC database to identify the potential hTERT inhibitors
por: Afzaal, Hasan, et al.
Publicado: (2022)

Advances in mitophagy and mitochondrial apoptosis pathway-related drugs in glioblastoma treatment
por: Li, Weiping, et al.
Publicado: (2023)

Lead Optimization of Dehydroemetine for Repositioned Use in Malaria
por: Panwar, Priyanka, et al.
Publicado: (2020)

Blood Immune Cell Composition Associated with Obesity and Drug Repositioning Revealed by Epigenetic and Transcriptomic Conjoint Analysis
por: Liu, Jia-Chen, et al.
Publicado: (2021)

Drug Repositioning for the Prevention and Treatment of Chemotherapy-Induced Peripheral Neuropathy: A Mechanism- and Screening-Based Strategy
por: Yamamoto, Shota, et al.
Publicado: (2021)

Corrigendum: Blood Immune Cell Composition Associated With Obesity and Drug Repositioning Revealed by Epigenetic and Transcriptomic Conjoint Analysis
por: Liu, Jia-Chen, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4rrtgs97oi7mt4pgo58f50eud4