Cargando…

Deregulation of ATG9A by impaired AR signaling induces autophagy in prostate stromal fibroblasts and promotes BPH progression

The activation of androgen receptor (AR) signaling plays an essential role in both prostate stromal cells and epithelial cells during the development of benign prostatic hyperplasia (BPH). Here we demonstrated that androgen ablation after 5α-reductase inhibitor (5-ARI) treatment induced autophagy in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Chen-Yi, Yang, Bo-Yu, Zhao, Sheng, Shao, Si-Hui, Bei, Xiao-Yu, Shi, Fei, Sun, Qian, Deng, Zheng, Wang, Xiao-Hai, Han, Bang-Min, Zhao, Fu-Jun, Xia, Shu-Jie, Ruan, Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864884/ https://www.ncbi.nlm.nih.gov/pubmed/29568063 http://dx.doi.org/10.1038/s41419-018-0415-2

Ejemplares similares

BPH and prostate cancer risk
por: Miah, Saiful, et al.
Publicado: (2014)

Atg38-Atg8 interaction in fission yeast establishes a positive feedback loop to promote autophagy
por: Yu, Zhong-Qiu, et al.
Publicado: (2020)

Dual roles of Atg8−PE deconjugation by Atg4 in autophagy
por: Yu, Zhong-Qiu, et al.
Publicado: (2012)

SIRT7 depletion inhibits cell proliferation and androgen-induced autophagy by suppressing the AR signaling in prostate cancer
por: Ding, Mao, et al.
Publicado: (2020)

Effects of Fungicide Propiconazole on the Yeast-Like Symbiotes in Brown Planthopper (BPH, Nilaparvata lugens Stål) and Its Role in Controlling BPH Infestation
por: Shentu, Xuping, et al.
Publicado: (2019)

5‐ARI induces autophagy of prostate epithelial cells through suppressing IGF‐1 expression in prostate fibroblasts
por: Yang, Bo‐Yu, et al.
Publicado: (2019)

Inflammasomes are important mediators of prostatic inflammation associated with BPH
por: Kashyap, Mahendra, et al.
Publicado: (2015)

Development of Interpretable Predictive Models for BPH and Prostate Cancer
por: Bermejo, Pablo, et al.
Publicado: (2015)

Minimally Invasive Treatment in Benign Prostatic Hyperplasia (BPH)
por: Sciacqua, L. V., et al.
Publicado: (2023)

Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structures
por: Kaiser, Stephen E., et al.
Publicado: (2012)

Phosphorylation of Atg31 is required for autophagy
por: Feng, Wenzhi, et al.
Publicado: (2015)

Management of BPH then 2000 and now 2016 – From BPH to BPO
por: Braeckman, Johan, et al.
Publicado: (2017)

Oxidation of Atg3 and Atg7 mediates inhibition of autophagy
por: Frudd, Karen, et al.
Publicado: (2018)

Molecular Characterization and Functional Analysis of Three Autophagy Genes, BxATG5, BxATG9, and BxATG16, in Bursaphelenchus xylophilus
por: Liu, Hong-Bin, et al.
Publicado: (2019)

Closing the loop: Three musketeers of autophagy-ATG2, ATG18a, and ATG9
por: Mishra, Divya
Publicado: (2023)

Resistance to Nilaparvata lugens in rice lines introgressed with the resistance genes Bph14 and Bph15 and related resistance types
por: Han, Yongqiang, et al.
Publicado: (2018)

Uba1 functions in Atg7- and Atg3-independent autophagy
por: Chang, Tsun-Kai, et al.
Publicado: (2013)

Atg11 tethers Atg9 vesicles to initiate selective autophagy
por: Matscheko, Nena, et al.
Publicado: (2019)

Clinical Implications of Residual Urine in Korean Benign Prostatic Hyperplasia (BPH) Patients: A Prognostic Factor for BPH-Related Clinical Events
por: Ko, Young Hwii, et al.
Publicado: (2010)

Stromal TGF-β signaling induces AR activation in prostate cancer
por: Yang, Feng, et al.
Publicado: (2014)

Molecular Breeding of Rice Restorer Lines and Hybrids for Brown Planthopper (BPH) Resistance Using the Bph14 and Bph15 Genes
por: Wang, Hongbo, et al.
Publicado: (2016)

BPH management today
por: Mangera, Altaf, et al.
Publicado: (2014)

Assessment of BPH/BOO
por: Mangera, Altaf, et al.
Publicado: (2014)

Restoration of the ATG5-dependent autophagy sensitizes DU145 prostate cancer cells to chemotherapeutic drugs
por: Peng, Ke, et al.
Publicado: (2021)

Stromal AR inhibits prostate tumor progression by restraining secretory luminal epithelial cells
por: Liu, Yueli, et al.
Publicado: (2022)

Marker assisted pyramiding of Bph6 and Bph9 into elite restorer line 93–11 and development of functional marker for Bph9
por: Wang, Yang, et al.
Publicado: (2017)

The Role of TURP in the Detection of Prostate Cancer in BPH Patients with Previously Negative Prostate Biopsy
por: Kim, Dae Keun, et al.
Publicado: (2010)

Androgen Regulated Genes in Human Prostate Xenografts in Mice: Relation to BPH and Prostate Cancer
por: Love, Harold D., et al.
Publicado: (2009)

Prostatic ischemia induces ventral prostatic hyperplasia in the SHR; possible mechanism of development of BPH
por: Saito, Motoaki, et al.
Publicado: (2014)

Bladder stone secondary to prostatic urethral lift (PUL) for benign prostatic hyperplasia (BPH)
por: Kang, JiHun
Publicado: (2021)

The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy
por: Rao, Yijian, et al.
Publicado: (2016)

BIRC5/Survivin is a novel ATG12–ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells
por: Lin, Tzu-Yu, et al.
Publicado: (2019)

Atg1 kinase in fission yeast is activated by Atg11-mediated dimerization and cis-autophosphorylation
por: Pan, Zhao-Qian, et al.
Publicado: (2020)

Recent advances in prostate cancer and BPH : the proceedings of the IV Congress on Progress and Controversies in Oncological Urology (PACIOU IV), held in Rotterdam, the Netherlands, April 1996 /
Publicado: (1997)

Autophagy is deregulated in cancer-associated fibroblasts from oral cancer and is stimulated during the induction of fibroblast senescence by TGF-β1
por: Tan, May Leng, et al.
Publicado: (2021)

LIM domain only 2 over-expression in prostate stromal cells facilitates prostate cancer progression through paracrine of Interleukin-11
por: Jiang, Chen-Yi, et al.
Publicado: (2016)

Clinical significance of EPHX2 deregulation in prostate cancer
por: Liu, Ming-Sheng, et al.
Publicado: (2020)

ATG5 Is Essential for ATG8-Dependent Autophagy and Mitochondrial Homeostasis in Leishmania major
por: Williams, Roderick A. M., et al.
Publicado: (2012)

Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase
por: Papinski, Daniel, et al.
Publicado: (2014)

Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase
por: Papinski, Daniel, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_uhdh74l6kgocqf807o7nllf2di