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Heterogeneous Cytoskeletal Force Distribution Delineates the Onset Ca(2+) Influx Under Fluid Shear Stress in Astrocytes
Mechanical perturbations increase intracellular Ca(2+) in cells, but the coupling of mechanical forces to the Ca(2+) influx is not well understood. We used a microfluidic chamber driven with a high-speed pressure servo to generate defined fluid shear stress to cultured astrocytes, and simultaneously...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864927/ https://www.ncbi.nlm.nih.gov/pubmed/29615869 http://dx.doi.org/10.3389/fncel.2018.00069 |