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Rac1 in podocytes promotes glomerular repair and limits the formation of sclerosis

Rac1, a Rho family member, is ubiquitously expressed and participates in various biological processes. Rac1 expression is induced early in podocyte injury, but its role in repair is unclear. To investigate the role of Rac1 expression in podocytes under pathological conditions, we used podocyte-speci...

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Detalles Bibliográficos
Autores principales: Asao, Rin, Seki, Takuto, Takagi, Miyuki, Yamada, Hiroyuki, Kodama, Fumiko, Hosoe-Nagai, Yoshiko, Tanaka, Eriko, Trejo, Juan Alejandro Oliva, Yamamoto-Nonaka, Kanae, Sasaki, Yu, Hidaka, Teruo, Ueno, Takashi, Yanagita, Motoko, Suzuki, Yusuke, Tomino, Yasuhiko, Asanuma, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864960/
https://www.ncbi.nlm.nih.gov/pubmed/29567961
http://dx.doi.org/10.1038/s41598-018-23278-6