Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids

Cell-free protein synthesis has emerged as a powerful approach for expanding the range of genetically encoded chemistry into proteins. Unfortunately, efforts to site-specifically incorporate multiple non-canonical amino acids into proteins using crude extract-based cell-free systems have been limite...

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Detalles Bibliográficos
Autores principales: Martin, Rey W., Des Soye, Benjamin J., Kwon, Yong-Chan, Kay, Jennifer, Davis, Roderick G., Thomas, Paul M., Majewska, Natalia I., Chen, Cindy X., Marcum, Ryan D., Weiss, Mary Grace, Stoddart, Ashleigh E., Amiram, Miriam, Ranji Charna, Arnaz K., Patel, Jaymin R., Isaacs, Farren J., Kelleher, Neil L., Hong, Seok Hoon, Jewett, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865108/
https://www.ncbi.nlm.nih.gov/pubmed/29572528
http://dx.doi.org/10.1038/s41467-018-03469-5

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