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Structure and evolution of the Fam20 kinases

The Fam20 proteins are novel kinases that phosphorylate secreted proteins and proteoglycans. Fam20C phosphorylates hundreds of secreted proteins and is activated by the pseudokinase Fam20A. Fam20B phosphorylates a xylose residue to regulate proteoglycan synthesis. Despite these wide-ranging and impo...

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Detalles Bibliográficos
Autores principales:	Zhang, Hui, Zhu, Qinyu, Cui, Jixin, Wang, Yuxin, Chen, Mark J., Guo, Xing, Tagliabracci, Vincent S., Dixon, Jack E., Xiao, Junyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865150/ https://www.ncbi.nlm.nih.gov/pubmed/29572475 http://dx.doi.org/10.1038/s41467-018-03615-z

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