Poly-ligand profiling differentiates trastuzumab-treated breast cancer patients according to their outcomes

Assessing the phenotypic diversity underlying tumour progression requires the identification of variations in the respective molecular interaction networks. Here we report proof-of-concept for a platform called poly-ligand profiling (PLP) that surveys these system states and distinguishes breast can...

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Detalles Bibliográficos
Autores principales: Domenyuk, Valeriy, Gatalica, Zoran, Santhanam, Radhika, Wei, Xixi, Stark, Adam, Kennedy, Patrick, Toussaint, Brandon, Levenberg, Symon, Wang, Jie, Xiao, Nianqing, Greil, Richard, Rinnerthaler, Gabriel, Gampenrieder, Simon P., Heimberger, Amy B., Berry, Donald A., Barker, Anna, Quackenbush, John, Marshall, John L., Poste, George, Vacirca, Jeffrey L., Vidal, Gregory A., Schwartzberg, Lee S., Halbert, David D., Voss, Andreas, Magee, Daniel, Miglarese, Mark R., Famulok, Michael, Mayer, Günter, Spetzler, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865185/
https://www.ncbi.nlm.nih.gov/pubmed/29572535
http://dx.doi.org/10.1038/s41467-018-03631-z

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