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Linear and inverted U-shaped dose-response functions describe estrogen effects on hippocampal activity in young women

In animals, 17-beta-estradiol (E2) enhances hippocampal plasticity in a dose-dependent, monotonically increasing manner, but this relationship can also exhibit an inverted U-shaped function. To investigate E2’s dose-response function in the human hippocampus, we pharmacologically increased E2 levels...

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Detalles Bibliográficos
Autores principales:	Bayer, Janine, Gläscher, Jan, Finsterbusch, Jürgen, Schulte, Laura H., Sommer, Tobias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865215/ https://www.ncbi.nlm.nih.gov/pubmed/29572476 http://dx.doi.org/10.1038/s41467-018-03679-x

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