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Chronic oxycodone induces axonal degeneration in rat brain

BACKGROUND: Chronic opioid therapy for non-malignant pain conditions has significantly increased over the last 15 years. Recently, the correlation between opioid analgesics and alternations in brain structure, such as leukoencephalopathy, axon demyelination, and white matter lesions, has been demons...

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Detalles Bibliográficos
Autores principales:	Fan, Ruping, Schrott, Lisa M., Arnold, Thomas, Snelling, Stephen, Rao, Meghana, Graham, Derrel, Cornelius, Angela, Korneeva, Nadejda L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865283/ https://www.ncbi.nlm.nih.gov/pubmed/29571287 http://dx.doi.org/10.1186/s12868-018-0417-0

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