YM155 decreases radiation-induced invasion and reverses epithelial–mesenchymal transition by targeting STAT3 in glioblastoma

BACKGROUND: Radiotherapy constitutes a standard arm of therapy in the multimodal treatment of patients with glioblastoma (GBM). Ironically, studies have recently revealed that radiation can augment malignant progression, by promoting migration and invasion, which make the disease especially difficul...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Wang, Xuehai, Xu, Ran, Ji, Jianxiong, Xu, Yangyang, Han, Mingzhi, Wei, Yuzhen, Huang, Bin, Chen, Anjing, Zhang, Qing, Li, Wenjie, Wang, Jian, Li, Xingang, Qiu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865331/
https://www.ncbi.nlm.nih.gov/pubmed/29571296
http://dx.doi.org/10.1186/s12967-018-1451-5

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