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Renal autoregulation and blood pressure management in circulatory shock

The importance of personalized blood pressure management is well recognized. Because renal pressure–flow relationships may vary among patients, understanding how renal autoregulation may influence blood pressure control is essential. However, much remains uncertain regarding the determinants of rena...

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Detalles Bibliográficos
Autores principales: Post, Emiel Hendrik, Vincent, Jean-Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865356/
https://www.ncbi.nlm.nih.gov/pubmed/29566705
http://dx.doi.org/10.1186/s13054-018-1962-8
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author Post, Emiel Hendrik
Vincent, Jean-Louis
author_facet Post, Emiel Hendrik
Vincent, Jean-Louis
author_sort Post, Emiel Hendrik
collection PubMed
description The importance of personalized blood pressure management is well recognized. Because renal pressure–flow relationships may vary among patients, understanding how renal autoregulation may influence blood pressure control is essential. However, much remains uncertain regarding the determinants of renal autoregulation in circulatory shock, including the influence of comorbidities and the effects of vasopressor treatment. We review published studies on renal autoregulation relevant to the management of acutely ill patients with shock. We delineate the main signaling pathways of renal autoregulation, discuss how it can be assessed, and describe the renal autoregulatory alterations associated with chronic disease and with shock.
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spelling pubmed-58653562018-03-27 Renal autoregulation and blood pressure management in circulatory shock Post, Emiel Hendrik Vincent, Jean-Louis Crit Care Review The importance of personalized blood pressure management is well recognized. Because renal pressure–flow relationships may vary among patients, understanding how renal autoregulation may influence blood pressure control is essential. However, much remains uncertain regarding the determinants of renal autoregulation in circulatory shock, including the influence of comorbidities and the effects of vasopressor treatment. We review published studies on renal autoregulation relevant to the management of acutely ill patients with shock. We delineate the main signaling pathways of renal autoregulation, discuss how it can be assessed, and describe the renal autoregulatory alterations associated with chronic disease and with shock. BioMed Central 2018-03-22 /pmc/articles/PMC5865356/ /pubmed/29566705 http://dx.doi.org/10.1186/s13054-018-1962-8 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Post, Emiel Hendrik
Vincent, Jean-Louis
Renal autoregulation and blood pressure management in circulatory shock
title Renal autoregulation and blood pressure management in circulatory shock
title_full Renal autoregulation and blood pressure management in circulatory shock
title_fullStr Renal autoregulation and blood pressure management in circulatory shock
title_full_unstemmed Renal autoregulation and blood pressure management in circulatory shock
title_short Renal autoregulation and blood pressure management in circulatory shock
title_sort renal autoregulation and blood pressure management in circulatory shock
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865356/
https://www.ncbi.nlm.nih.gov/pubmed/29566705
http://dx.doi.org/10.1186/s13054-018-1962-8
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